Friedrich Ivar, Simm Andreas, Kötting Joachim, Thölen Frank, Fischer Burkhard, Silber Rolf-Edgar
Klinik für Herz- und Thoraxchirurgie, Universitätsklinikum Halle, Halle, Germany.
Dtsch Arztebl Int. 2009 Jun;106(25):416-22. doi: 10.3238/arztebl.2009.0416. Epub 2009 Jun 19.
As life expectancies rise and the number of persons over age 75 in the population increases, the proper treatment of elderly cardiac patients is becoming a matter of ever greater medical and political importance.
In collaboration with the German Federal Quality Assurance Office (Bundesgeschäftsstelle Qualitätssicherung, BQS), the authors analyzed the risk profiles of elderly patients by means of data sets from all cardiac surgical centers in Germany for the year 2007. The results regarding risk distribution and the morbidity and lethality statistics for isolated coronary surgery were derived from the complete, nationwide BQS data pool, containing information on a total of 47,881 operations. Data on quality of life and long-term survival were obtained from a selective literature search using Medline.
Compared to patients under age 65, those over age 75 have significantly more prognosis-determining comorbidities and risk factors. Accordingly, complication rates and lethality are higher in the latter age group (for example, there is a 4.3-fold relative risk elevation for renal dysfunction, a 3.0-fold elevation for neurological complications, and 3.7-fold elevation for in-hospital lethality). The patient's chronological age is a risk factor for lethality and morbidity after coronary surgical procedures.
The lethality risk of a bypass operation can be predicted very accurately with the aid of modern scoring systems. Successful cardiac surgical procedures can return the patient to a normal life expectancy and quality of life for his or her age group.
随着预期寿命的延长以及75岁以上人口数量的增加,老年心脏病患者的恰当治疗正成为一个在医学和政治上愈发重要的问题。
作者与德国联邦质量保证办公室(Bundesgeschäftsstelle Qualitätssicherung,BQS)合作,通过德国所有心脏外科中心2007年的数据集分析老年患者的风险概况。关于单纯冠状动脉手术的风险分布以及发病率和死亡率统计结果源自完整的全国性BQS数据库,该数据库包含总共47,881例手术的信息。生活质量和长期生存的数据通过使用Medline进行选择性文献检索获得。
与65岁以下的患者相比,75岁以上的患者具有更多显著影响预后的合并症和风险因素。相应地,后一年龄组的并发症发生率和死亡率更高(例如,肾功能不全的相对风险升高4.3倍,神经并发症升高3.0倍,院内死亡率升高3.7倍)。患者的实际年龄是冠状动脉手术后死亡率和发病率的一个风险因素。
借助现代评分系统可以非常准确地预测搭桥手术的死亡风险。成功的心脏外科手术可以使患者恢复到与其年龄组相适应的正常预期寿命和生活质量。