西班牙无乳链球菌对大环内酯类、林可酰胺类和酮内酯类耐药菌株的耐药机制及克隆关系的多中心研究
Multicenter study of the mechanisms of resistance and clonal relationships of Streptococcus agalactiae isolates resistant to macrolides, lincosamides, and ketolides in Spain.
作者信息
Gonzalez J J, Andreu A
机构信息
Servicio de Microbiología, Hospital Vall d'Hebron, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain.
出版信息
Antimicrob Agents Chemother. 2005 Jun;49(6):2525-7. doi: 10.1128/AAC.49.6.2525-2527.2005.
Abstract
Macrolide, lincosamide, and ketolide mechanisms of resistance and clonal relationships were characterized in a collection of 79 resistant group B streptococcus isolates obtained from neonates or pregnant women. The erm(B), erm(TR), and mef(A) genes were present in 62%, 30.4%, and 3.8% of the isolates, respectively. There was considerable clonal diversity among them.
摘要
在从新生儿或孕妇中分离出的79株B族链球菌耐药菌株中，对大环内酯类、林可酰胺类和酮内酯类的耐药机制及克隆关系进行了表征。erm(B)、erm(TR)和mef(A)基因分别存在于62%、30.4%和3.8%的分离株中。它们之间存在相当大的克隆多样性。
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