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加纳林婴猴(Otolemur garnettii)对迁移应激的皮质醇反应。

Cortisol response to relocation stress in Garnett's bushbaby (Otolemur garnettii).

作者信息

Watson Sheree L, McCoy John G, Stavisky Ronda C, Greer Tammy F, Hanbury David

机构信息

Department of Psychology, University of Southern Mississippi, Hattiesburg, Mississippi 39402-5025, USA.

出版信息

Contemp Top Lab Anim Sci. 2005 May;44(3):22-4.

Abstract

Relocation of research animals, either within a facility or from one facility to another, is assumed to be stressful. Development of appropriate research methodologies may be facilitated by understanding the extent and duration of the physiological response to relocation stress and whether the stress can be buffered by environmental or social factors, such as the presence of a cagemate. To characterize the response to relocation stress in Garnett's bushbaby, we assessed cortisol concentrations in nine female and six male bushbabies during relocation to a different facility; six of the animals were pair-housed at the time of the move and were moved with their respective cagemates. Fecal cortisol was assessed at three time points: 1) baseline (1 day prior to moving); 2) relocation (the day the animals were relocated); and 3) post-relocation (7 days after relocation). Cortisol concentrations were higher at the relocation time point than at baseline and post-relocation, which did not differ. Cortisol concentration did not differ as a function of having a cagemate during relocation. Although relocation resulted in a significant (P < 0.05) increase in cortisol excretion concentration, the levels returned to baseline within 7 days after the stressor.

摘要

研究动物的迁移,无论是在一个设施内还是从一个设施转移到另一个设施,都被认为会产生压力。了解对迁移应激的生理反应的程度和持续时间,以及这种应激是否可以通过环境或社会因素(如同笼伙伴的存在)来缓冲,可能有助于开发适当的研究方法。为了描述加纳氏婴猴对迁移应激的反应,我们评估了9只雌性和6只雄性婴猴在转移到不同设施期间的皮质醇浓度;其中6只动物在转移时成对饲养,并与各自的同笼伙伴一起转移。在三个时间点评估粪便皮质醇:1)基线(转移前1天);2)迁移(动物转移当天);3)迁移后(迁移后7天)。迁移时间点的皮质醇浓度高于基线和迁移后,而后两者没有差异。皮质醇浓度在迁移期间是否有同笼伙伴方面没有差异。尽管迁移导致皮质醇排泄浓度显著(P < 0.05)增加,但应激源出现后7天内水平恢复到基线。

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