Wu Chao-Chuan, Chou Pai-Yu, Hu Chi-Tan, Liu Zuo-Chai, Lin Chih-Yung, Tseng Yi-Hsiung, Lin Nien-Tsung
Department of Surgery, Tzu Chi University, Hualien 970, Taiwan.
J Clin Microbiol. 2005 Jun;43(6):2913-5. doi: 10.1128/JCM.43.6.2913-2915.2005.
The genotypes of Helicobacter pylori flaA, cagA, vacA, and iceA were determined for DNA isolated from patients with chronic gastritis or peptic ulcer in eastern Taiwan. The vacA gene encoding the s1a subtype was found to predominate in peptic ulcer patients, and the iceA1 genotype was associated with chronic gastritis. cagA and flaA genes were not found to be associated with these types of disease.
对从台湾东部慢性胃炎或消化性溃疡患者中分离出的DNA进行了幽门螺杆菌flaA、cagA、vacA和iceA基因分型。发现编码s1a亚型的vacA基因在消化性溃疡患者中占主导地位,iceA1基因型与慢性胃炎相关。未发现cagA和flaA基因与这些疾病类型相关。