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Terminalia arjuna(一种心脏保护药物)中的齐墩果烷三萜类化合物对呼吸爆发过程的影响。

Effect of oleanane triterpenoids from Terminalia arjuna--a cardioprotective drug on the process of respiratory oxyburst.

作者信息

Pawar R S, Bhutani K K

机构信息

Department of Natural Products, National Institute of Pharmaceutical Education and Research, Sect. 67, S.A.S. Nagar, Phase X, (Mohali), Punjab, India.

出版信息

Phytomedicine. 2005 May;12(5):391-3. doi: 10.1016/j.phymed.2003.11.007.

DOI:10.1016/j.phymed.2003.11.007
PMID:15957375
Abstract

The oleanane triterpenes arjunic acid, arjungenin and their glucosides, arjunetin and arjunglucoside II, were isolated from the bark of Terminalia arjuna. Arjungenin and its glucoside exhibited a moderate free radical scavenging activity while all the compounds showed no effect on the superoxide release from PMN cells. Further arjungenin also exhibited greater inhibitory action on the hypochlorous acid production from human neutrophils.

摘要

从诃子树皮中分离出了齐墩果烷三萜类化合物如阿朱那酸、阿朱那苷元及其糖苷阿朱那亭和阿朱那糖苷II。阿朱那苷元及其糖苷表现出适度的自由基清除活性,而所有这些化合物对中性粒细胞释放超氧阴离子均无影响。此外,阿朱那苷元对人中性粒细胞产生次氯酸也表现出更强的抑制作用。

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