Dawé Amadou, Talom Benjamin, Kapche Gilbert Deccaux Wabo Fotso, Siddiqui Kauser, Yakai Fawai, Talla Emmanuel, Shaiq Muhammad Ali, Lubna Iqbal, Ngadjui Bonabenture Tchaleu
Department of Chemistry, Higher Teachers Training College, University of Maroua, P.O. Box 55, Maroua, Cameroon.
Department of Chemistry, Faculty of Science, University of Ngaoundéré, P.O. Box 454, Ngaoundéré, Cameroon.
Z Naturforsch C J Biosci. 2017 May 1;72(5-6):203-208. doi: 10.1515/znc-2016-0178.
Termiglaucescin (1), a new triterpene glucoside, has been isolated from the ethyl acetate extract of the root bark of Terminalia glaucescens Planch. ex Benth, together with 11 known compounds, β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (2), arjunglucoside I (3), sericoside (4), arjungenin (5), sericic acid (6), arjunetin (7), chebuloside II (8), 3,3',4-tri-O-methylelagic acid (9), 3,3'-di-O-methylelagic acid (10), β-sitosterol (11) and stigmasterol (12). Compounds 2, 3, 7, 8 and 9 are reported from the plant for the first time. The structures of the isolated compounds were characterized by spectroscopic data interpretations, especially 1D and 2D NMR. The triterpenic isolates showed potent antioxidant and anti-inflammatory activities.
从毛诃子（Terminalia glaucescens Planch. ex Benth）根皮的乙酸乙酯提取物中分离得到了一种新的三萜糖苷——诃子新苷（1），以及11种已知化合物，分别为β-D-吡喃葡萄糖基-2α,3β,6β-三羟基-23-没食子酰基齐墩果-12-烯-28-酸酯（2）、诃子葡糖苷I（3）、绢毛诃子苷（4）、诃子宁（5）、绢毛诃子酸（6）、诃子亭（7）、诃子二糖苷II（8）、3,3',4-三-O-甲基鞣花酸（9）、3,3'-二-O-甲基鞣花酸（10）、β-谷甾醇（11）和豆甾醇（12）。化合物2、3、7、8和9首次从该植物中报道。通过光谱数据解析，尤其是一维和二维核磁共振，对分离得到的化合物结构进行了表征。三萜类分离物显示出较强的抗氧化和抗炎活性。
