Michet C J, Mason T G, Mazlumzadeh M
Division of Rheumatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Ann Rheum Dis. 2005 Jul;64(7):1068-70. doi: 10.1136/ard.2004.022228.
To determine the natural history of hip joint disease in psoriatic arthritis (PsA) and identify clinical risk factors for its early identification.
504 patients with PsA according to ESSG criteria were studied. Mean follow up was 5.7 years (range <1-45). Mean age at onset of psoriasis was 32 years and of PsA, 39 years. The most common pattern of PsA at onset was oligoarticular (49%) and at the latest examination, polyarticular (65%). Sacroiliitis or spondylitis was diagnosed in 94 (18.7%) patients.
32 (6.3%) patients developed psoriatic hip arthropathy, and of these, 26 (81%) also had sacroiliitis or spondylitis. In 7/17 (41%) patients the hip became affected within 1 year after the onset of PsA. Hip disease occurred more often in younger patients. Sex, pattern of peripheral arthritis, duration of psoriasis before arthritis affected the distal interphalangeal joints, dactylitis, or enthesitis were not associated with the risk of hip disease. Seventeen patients were followed up and nine required hip arthroplasty. Sixteen (50%) first had arthroplasty within 5 years after the onset of hip pain.
Psoriatic hip arthropathy occurs infrequently in PsA and is associated with earlier onset of arthritis and psoriatic spondylitis. Bilateral hip involvement and rapid progression to hip arthroplasty are common.
确定银屑病关节炎(PsA)中髋关节疾病的自然病程,并识别早期诊断的临床危险因素。
根据欧洲脊柱关节病研究组(ESSG)标准对504例PsA患者进行研究。平均随访时间为5.7年(范围<1 - 45年)。银屑病发病的平均年龄为32岁,PsA发病的平均年龄为39岁。PsA发病时最常见的类型是少关节型(49%),而在最近一次检查时,多关节型(65%)。94例(18.7%)患者被诊断为骶髂关节炎或脊柱炎。
32例(6.3%)患者发生了银屑病性髋关节病,其中26例(81%)也患有骶髂关节炎或脊柱炎。在17例患者中有7例(41%)在PsA发病后1年内髋关节受累。髋关节疾病在年轻患者中更常见。性别、外周关节炎类型、关节炎发病前银屑病的病程、远端指间关节受累情况、指(趾)炎或附着点炎与髋关节疾病风险无关。17例患者接受随访,9例需要进行髋关节置换术。16例(50%)在髋关节疼痛发作后5年内首次进行了关节置换术。
银屑病性髋关节病在PsA中发生率较低,且与关节炎和银屑病性脊柱炎的较早发病相关。双侧髋关节受累以及快速进展至髋关节置换术较为常见。