Spielmeyer W, McIntosh R A, Kolmer J, Lagudah E S
CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia.
Theor Appl Genet. 2005 Aug;111(4):731-5. doi: 10.1007/s00122-005-2058-9. Epub 2005 Jun 18.
The incorporation of effective and durable disease resistance is an important breeding objective for wheat improvement. The leaf rust resistance gene Lr34 and stripe rust resistance gene Yr18 are effective at the adult plant stage and have provided moderate levels of durable resistance to leaf rust caused by Puccinia triticina Eriks. and to stripe rust caused by Puccinia striiformis Westend. f. sp. tritici. These genes have not been separated by recombination and map to chromosome 7DS in wheat. In a population of 110 F(7) lines derived from a Thatcher x Thatcher isogenic line with Lr34/Yr18, field resistance to leaf rust conferred by Lr34 and to stripe rust resistance conferred by Yr18 cosegregated with adult plant resistance to powdery mildew caused by Blumeria graminis (DC) EO Speer f. sp. tritici. Lr34 and Yr18 were previously shown to be associated with enhanced stem rust resistance and tolerance to barley yellow dwarf virus infection. This chromosomal region in wheat has now been linked with resistance to five different pathogens. The Lr34/Yr18 phenotypes and associated powdery mildew resistance were mapped to a single locus flanked by microsatellite loci Xgwm1220 and Xgwm295 on chromosome 7DS.
导入有效且持久的抗病性是小麦改良的一项重要育种目标。抗叶锈病基因Lr34和抗条锈病基因Yr18在成株期有效，对由小麦叶锈菌（Puccinia triticina Eriks.）引起的叶锈病以及由条形柄锈菌小麦专化型（Puccinia striiformis Westend. f. sp. tritici）引起的条锈病提供了中等水平的持久抗性。这些基因尚未通过重组分离，在小麦中定位到7DS染色体上。在一个由撒切尔小麦与携带Lr34/Yr18的撒切尔近等基因系杂交衍生的110个F(7)株系群体中，Lr34赋予的对叶锈病的田间抗性和Yr18赋予的对条锈病的抗性与对由小麦白粉菌（Blumeria graminis (DC) EO Speer f. sp. tritici）引起的白粉病的成株抗性共分离。Lr34和Yr18先前已被证明与增强的抗秆锈病能力以及对大麦黄矮病毒感染的耐受性有关。小麦中的这个染色体区域现在已与对五种不同病原体的抗性相关联。Lr34/Yr18的表型以及相关的白粉病抗性被定位到7DS染色体上由微卫星位点Xgwm1220和Xgwm295侧翼的一个单一基因座。
