Synthesis, characterisation and cytotoxicity of chloro derivatives of prenylnaphthohydroquinone.

作者信息

Molinari Aurora, Oliva Alfonso, Ojeda Claudia, Escobar Jorge, Gallardo Carolina, Miguel del Corral José Ma, Castro Ma Angeles, Cuevas Carmen, San Feliciano Arturo

机构信息

Instituto de Química, Pontificia Universidad Católica de Valparaíso, Casilla 4059 Valparaíso, Chile.

出版信息

Bioorg Med Chem. 2005 Jun 1;13(11):3841-6. doi: 10.1016/j.bmc.2005.02.063.

DOI:10.1016/j.bmc.2005.02.063

PMID:15966071

Abstract

From the Diels-Alder adduct between alpha-myrcene and 2-chloro-1,4-benzoquinone, a family of chloro derivatives of prenylnaphthohydroquinone have been synthesised and evaluated for their cytotoxicity against 14 neoplastic cell lines.

摘要