Hirsch Katrin, Ludwig Ralf J, Wolter Manfred, Zollner Thomas M, Hardt Katja, Kaufmann Roland, Boehncke Wolf-Henning
Dept. of Dermatology, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, Frankfurt am Main, Germany.
J Dtsch Dermatol Ges. 2005 Jul;3(7):530-1. doi: 10.1111/j.1610-0387.2005.05726.x.
Eosinophilic cellulitis (Wells' syndrome) is an inflammatory dermatosis characterized by marked eosinophilic infiltrates. Drugs and various infections are recognized causes of eosinophilic cellulitis. Eosinophilic cellulitis has been reported in non-hematological malignancies in two patients with squamous cell carcinoma and one with nasopharyngeal carcinoma. We report the association of eosinophilic cellulitis with adenocarcinoma of the colon. Curative hemicolectomy led to a complete remission, suggesting that underlying malignancies can trigger eosinophilic cellulitis.
嗜酸性粒细胞性蜂窝织炎(韦尔斯综合征)是一种以显著嗜酸性粒细胞浸润为特征的炎症性皮肤病。药物和各种感染是公认的嗜酸性粒细胞性蜂窝织炎的病因。在两名鳞状细胞癌患者和一名鼻咽癌患者的非血液系统恶性肿瘤中曾有嗜酸性粒细胞性蜂窝织炎的报道。我们报告了嗜酸性粒细胞性蜂窝织炎与结肠癌的关联。根治性半结肠切除术导致完全缓解,提示潜在的恶性肿瘤可引发嗜酸性粒细胞性蜂窝织炎。