Janssen Caroline, Lauwers Noémie, Leysen Inge
Department of Ophthalmology, University Hospital of Antwerp, Edegem, Belgium.
Ocul Oncol Pathol. 2021 Jun;7(3):190-193. doi: 10.1159/000511595. Epub 2021 Jan 28.
We present a case of a woman with a swollen upper eyelid in ptosis, conjunctival nodules, and chemosis present for a couple of weeks. She did not respond to therapy for hordeolum or allergy. A biopsy followed by histopathological examination showed a large infiltration of eosinophilic granulocytes and flame figures, so the diagnosis of Wells syndrome was made. Oral methylprednisolone in high dose was necessary, and tapering was slow because of frequent bouts of relapse. After 3 months, the swelling and hard feeling of the eyelid disappeared, but a slight ptosis remained. Eyelid swelling and eosinophilia recurred 18 months after resolution of the first episode.
我们报告一例女性病例,该患者上睑肿胀伴上睑下垂、结膜结节及球结膜水肿,持续数周。她对睑腺炎或过敏治疗均无反应。活检及组织病理学检查显示大量嗜酸性粒细胞浸润及火焰状图形,因此诊断为韦尔斯综合征。需要使用高剂量口服甲泼尼龙,且由于频繁复发,减量过程缓慢。3个月后,眼睑肿胀及硬结感消失,但仍遗留轻度上睑下垂。首次发作缓解18个月后,眼睑肿胀及嗜酸性粒细胞增多再次出现。