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唾液皮质醇——噪声研究中用于探究应激效应的一种新方法。

Saliva cortisol--a new approach in noise research to study stress effects.

作者信息

Bigert Carolina, Bluhm Gösta, Theorell Töres

机构信息

Department of Occupational and Environmental Health, Norrbacka, Karolinska Hospital, SE-171 76 Stockholm, Sweden.

出版信息

Int J Hyg Environ Health. 2005;208(3):227-30. doi: 10.1016/j.ijheh.2005.01.014.

Abstract

Several studies have indicated an association between noise exposure and cardiovascular disease. A noise-induced release of stress hormones has been considered to be a biological pathway of importance in this respect. The described method is of special interest since concentration of cortisol in saliva reflects the concentration of free cortisol in serum and repeated saliva samples can easily be collected. Our objective is to overview the use of saliva cortisol to measure stress in relation to noise as a tool for research on noise-related cardiovascular risk. Previous studies of saliva cortisol in relation to noise exposure are reviewed. In summary, repeated assessments of saliva cortisol seems to be a feasible method to apply in field studies in noise research.

摘要

多项研究表明,噪声暴露与心血管疾病之间存在关联。在这方面,噪声诱导的应激激素释放被认为是一条重要的生物学途径。所描述的方法特别值得关注,因为唾液中皮质醇的浓度反映了血清中游离皮质醇的浓度,并且可以轻松收集重复的唾液样本。我们的目标是概述使用唾液皮质醇来测量与噪声相关的应激,作为研究噪声相关心血管风险的一种工具。本文回顾了以往关于唾液皮质醇与噪声暴露关系的研究。总之,重复评估唾液皮质醇似乎是一种适用于噪声研究现场调查的可行方法。

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