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严重肠道吸收不良的患者碘状态无变化。

Patients with severe bowel malabsorption do not have changes in iodine status.

作者信息

Navarro Anderson Marilere, Suen Vivian Marques Miguel, Souza Isabel Machado, De Oliveira José Eduardo Dutra, Marchini Julio Sergio

机构信息

Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.

出版信息

Nutrition. 2005 Sep;21(9):895-900. doi: 10.1016/j.nut.2005.02.006.

DOI:10.1016/j.nut.2005.02.006
PMID:15979283
Abstract

OBJECTIVE

We evaluated the influence of intestinal malabsorption on iodine status in patients who had short gut syndrome and received total parenteral nutrition (group I) compared with control subjects who had eutrophia (group II) and patients who had other illnesses but normal digestive tracts (group III).

METHODS

Twenty-seven subjects were studied. Iodine intake was determined by the measurement of iodine in ingested food and in parenteral nutrition solutions. Urinary iodine excretion was measured by the Sandell-Kalthoff reaction. Urinary creatinine, anthropometric, and thyroid hormone functions were also determined.

RESULTS

Daily iodine intakes were 658 +/- 125 (mean +/- standard deviation), 573 +/- 204, and 629 +/- 208 microg for groups I, II, and III, respectively. Daily urinary iodine excretion levels were 399 +/- 308, 439 +/- 192, and 370 +/- 268 microg and ratios of urinary iodine (micrograms) to creatinine (grams) were 614 +/- 349, 354 +/- 142, and 483 +/- 292, respectively. There were no statistically significant differences across groups.

CONCLUSION

In Brazil the iodine provided by food, including iodized salt, has been sufficient to maintain iodine status in patients with short gut syndrome.

摘要

目的

我们评估了肠道吸收不良对短肠综合征患者碘状态的影响,这些患者接受了全胃肠外营养(第一组),并与营养正常的对照受试者(第二组)以及患有其他疾病但消化道正常的患者(第三组)进行比较。

方法

对27名受试者进行了研究。通过测量摄入食物和胃肠外营养溶液中的碘来确定碘摄入量。通过桑德尔 - 卡尔托夫反应测量尿碘排泄量。还测定了尿肌酐、人体测量指标和甲状腺激素功能。

结果

第一组、第二组和第三组的每日碘摄入量分别为658±125(平均值±标准差)、573±204和629±208微克。每日尿碘排泄水平分别为399±308、439±192和370±268微克,尿碘(微克)与肌酐(克)的比值分别为614±349、354±142和483±292。各组之间无统计学显著差异。

结论

在巴西,包括加碘盐在内的食物所提供的碘足以维持短肠综合征患者的碘状态。

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