DIAL：一个用于自动识别蛋白质结构域的基于网络的服务器。
DIAL: a web-based server for the automatic identification of structural domains in proteins.
作者信息
Pugalenthi Ganesan, Archunan Govindaraju, Sowdhamini Ramanathan
机构信息
National Centre for Biological Sciences, Tata Institute of Fundamental Research UAS-GKVK campus, Bellary Road, Bangalore 560 065, Karnataka, India.
出版信息
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W130-2. doi: 10.1093/nar/gki427.
Abstract
DIAL is a web server for the automatic identification of structural domains given the 3D coordinates of a protein. Delineation of the structural domains and their exact boundaries are the starting points for the better realization of distantly related members of the domain families, for the rational design of the experiments and for clearer understanding of the biological function. The current server can examine crystallographic multiple chains and provide structural domain solutions that can also describe domain swapping events. The server can be accessed from http://www.ncbs.res.in/~faculty/mini/DIAL/home.html. The Supplementary data can be accessed from http://www.ncbs.res.in/~faculty/mini/DIAL/supplement.html.
摘要
DIAL是一个网络服务器，用于在已知蛋白质三维坐标的情况下自动识别结构域。结构域的划分及其精确边界是更好地认识结构域家族中远距离相关成员、合理设计实验以及更清晰理解生物学功能的起点。当前的服务器能够检测晶体学中的多条链，并提供能够描述结构域交换事件的结构域解决方案。可通过http://www.ncbs.res.in/~faculty/mini/DIAL/home.html访问该服务器。补充数据可通过http://www.ncbs.res.in/~faculty/mini/DIAL/supplement.html获取。
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