Hu Zhenjun, Mellor Joe, Wu Jie, Yamada Takuji, Holloway Dustin, Delisi Charles
Program in Bioinformatics and Systems Biology, Boston University, 44 Cummington Street, Boston, MA 02215, USA.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W352-7. doi: 10.1093/nar/gki431.
VisANT is a web-based software framework for visualizing and analyzing many types of networks of biological interactions and associations. Networks are a useful computational tool for representing many types of biological data, such as biomolecular interactions, cellular pathways and functional modules. Given user-defined sets of interactions or groupings between genes or proteins, VisANT provides: (i) a visual interface for combining and annotating network data, (ii) supporting function and annotation data for different genomes from the Gene Ontology and KEGG databases and (iii) the statistical and analytical tools needed for extracting topological properties of the user-defined networks. Users can customize, modify, save and share network views with other users, and import basic network data representations from their own data sources, and from standard exchange formats such as PSI-MI and BioPAX. The software framework we employ also supports the development of more sophisticated visualization and analysis functions through its open API for Java-based plug-ins. VisANT is distributed freely via the web at http://visant.bu.edu and can also be downloaded for individual use.
VisANT是一个基于网络的软件框架，用于可视化和分析多种类型的生物相互作用和关联网络。网络是一种有用的计算工具，可用于表示多种类型的生物数据，如生物分子相互作用、细胞途径和功能模块。给定用户定义的基因或蛋白质之间的相互作用集或分组，VisANT提供：（i）用于组合和注释网络数据的可视化界面，（ii）来自基因本体论和KEGG数据库的不同基因组的支持功能和注释数据，以及（iii）提取用户定义网络的拓扑特性所需的统计和分析工具。用户可以自定义、修改、保存网络视图并与其他用户共享，还可以从自己的数据源以及PSI-MI和BioPAX等标准交换格式导入基本网络数据表示。我们使用的软件框架还通过其基于Java的插件的开放API支持开发更复杂的可视化和分析功能。VisANT可通过网络免费获取，网址为http://visant.bu.edu，也可下载供个人使用。
