Saebø A, Lassen J
Institute of Surgery, Bergen University Hospital, Norway.
J Intern Med. 1992 May;231(5):537-41. doi: 10.1111/j.1365-2796.1992.tb00970.x.
During the period 1974-1983, Yersinia enterocolitica infection was diagnosed in 458 hospitalized patients by antibody response or isolation of the micro-organism. Eight (1.75%) patients showed signs of acute pancreatitis with elevated serum or urine levels of amylase; two patients had acute insulin-dependent diabetes. The patients were followed up for 4-14 years (until 1987). Four patients were readmitted with chronic pancreatitis, and one with acute pancreatitis. Diabetes developed in two males and nine females; in seven cases this was associated with chronic conditions of possible autoimmune aetiology. In 1987 a significantly higher than expected prevalence of diabetes was demonstrated among female subjects aged 30-54 years. Yersinia enterocolitica infection constitutes a differential diagnosis in acute pancreatitis, and might be related to the development of chronic pancreatitis and diabetes.
在1974年至1983年期间，通过抗体反应或微生物分离，在458名住院患者中诊断出小肠结肠炎耶尔森菌感染。8名（1.75%）患者出现急性胰腺炎体征，血清或尿淀粉酶水平升高；2名患者患有急性胰岛素依赖型糖尿病。对这些患者进行了4至14年的随访（直至1987年）。4名患者因慢性胰腺炎再次入院，1名因急性胰腺炎再次入院。糖尿病在2名男性和9名女性中发生；在7例中，这与可能的自身免疫病因的慢性疾病有关。1987年，在30至54岁的女性受试者中，糖尿病患病率显著高于预期。小肠结肠炎耶尔森菌感染是急性胰腺炎的鉴别诊断之一，可能与慢性胰腺炎和糖尿病的发生有关。
