Baran Nergis V, Gürlü Vuslat P, Esgin Haluk
Department of Ophthalmology, Trakya University, Edirne, Turkey.
Clin Exp Ophthalmol. 2005 Aug;33(4):369-72. doi: 10.1111/j.1442-9071.2005.01027.x.
This study aimed to investigate the long-term effects of central serous chorioretinopathy (CSCR) on macular function.
Sixty-two eyes of 31 patients were included in this study. All patients were diagnosed with unilateral CSCR at the Retina Unit of the Ophthalmology Department, Trakya University Medical Faculty, and had a post-attack bilateral visual acuity of 6/6 and a follow-up period of a minimum of 6 months. Visual function was assessed using the Amsler grid, 40-hue colour discrimination test, visual field examination by means of Octopus automatic perimeter and Cambridge contrast sensitivity tests.
Of the 31 patients, 71% were men and 29% were women, with a mean age of 39.3 +/- 7.6 years. The patients had a mean follow-up period of 50.6 +/- 40.5 months after the acute attack. Metamorphopsia was observed in 67.7% of the cases with CSCR. A colour discrimination defect was found in 48.4% of the CSCR eyes and in 54.8% of the fellow eyes. As compared with the fellow eyes, the mean deviation in the central 10 degrees of visual field was significantly higher (t = 2.9, P = 0.007) and the mean contrast sensitivity score was significantly lower (t = -3.2, P = 0.004) in the CSCR eyes.
Patients with unilateral CSCR were observed to have long-term bilateral colour discrimination defects, and eyes with clinical CSCR were determined to have central relative scotoma and loss of contrast sensitivity.
本研究旨在调查中心性浆液性脉络膜视网膜病变（CSCR）对黄斑功能的长期影响。
本研究纳入了31例患者的62只眼。所有患者均在恰纳卡莱大学医学院眼科视网膜科被诊断为单侧CSCR，发作后双侧视力均为6/6，随访期至少6个月。使用Amsler方格表、40色调颜色辨别试验、Octopus自动视野计进行的视野检查以及剑桥对比敏感度测试评估视觉功能。
31例患者中，71%为男性，29%为女性，平均年龄为39.3±7.6岁。急性发作后患者的平均随访期为50.6±40.5个月。67.7%的CSCR病例出现视物变形。48.4%的CSCR患眼和54.8%的对侧眼发现有颜色辨别缺陷。与对侧眼相比，CSCR患眼中央10度视野的平均偏差显著更高（t = 2.9，P = 0.007），平均对比敏感度评分显著更低（t = -3.2，P = 0.004）。
观察到单侧CSCR患者存在长期双侧颜色辨别缺陷，临床诊断为CSCR的患眼存在中心相对暗点和对比敏感度丧失。
