Guix S, Bosch A, Pintó R M
Enteric Virus Group, Department of Microbiology, University of Barcelona, Barcelona, Spain.
Lett Appl Microbiol. 2005;41(2):103-5. doi: 10.1111/j.1472-765X.2005.01759.x.
Human astroviruses (HAstV) are important human pathogens causing gastroenteritis worldwide. The increased recognition of astroviruses as the cause of sporadic outbreaks of disease is due to the recent availability of improved diagnostic methods. During the last decade, most epidemiological surveys have chosen astrovirus-specific RT-PCR as screening methods. In addition to serotyping by molecular techniques, new typing methods are being developed that may also identify other viral properties related to virulence. The information provided by different typing assays is required for a better understanding of both the antigenic diversity and the molecular mechanisms of pathogenicity.
人星状病毒（HAstV）是导致全球范围内胃肠炎的重要人类病原体。星状病毒作为散发性疾病暴发原因的认知增加，归因于近期改进诊断方法的可得性。在过去十年中，大多数流行病学调查选择星状病毒特异性逆转录聚合酶链反应（RT-PCR）作为筛查方法。除了通过分子技术进行血清分型外，新的分型方法也在开发中，这些方法可能还会鉴定出与毒力相关的其他病毒特性。为了更好地理解抗原多样性和致病分子机制，需要不同分型检测提供的信息。
