Mitchell Paul, Lee Anne J, Wang Jie Jin, Rochtchina Elena
Department of Ophthalmology, University of Sydney, Australia.
Am J Ophthalmol. 2005 Jul;140(1):131-2. doi: 10.1016/j.ajo.2004.12.088.
To quantify the relation of blood pressure (BP) and intraocular pressure (IOP) across the clinical range of BP in an older phakic population not using glaucoma medications.
Cross-sectional population-based study
Seated BP and applanation IOP were measured, and their relation was assessed in regression models.
Mean IOP of the two eyes increased linearly from 14.3 mm Hg for systolic BP <110 mm Hg to 17.7 mm Hg for systolic BP > or =200 mm Hg, a 3.4-mm Hg excursion over this range. Mean IOP also increased from 15.2 mm Hg for diastolic BP <70 to 18.4 mm Hg for diastolic BP > or =120, a similar variance. There were no changes after age and multivariate adjustments for IOP or after excluding undiagnosed glaucoma cases.
A 3-mm linear IOP increase over the clinical spectrum of BP levels was evident; this variance is greater than with most other systemic and ocular parameters.
量化在未使用青光眼药物的老年有晶状体人群的血压临床范围内，血压（BP）与眼压（IOP）之间的关系。
基于人群的横断面研究
测量坐位血压和压平眼压，并在回归模型中评估它们之间的关系。
双眼平均眼压从收缩压<110mmHg时的14.3mmHg线性增加至收缩压≥200mmHg时的17.7mmHg，在此范围内变化3.4mmHg。平均眼压也从舒张压<70时的15.2mmHg增加至舒张压≥120时的18.4mmHg，变化相似。在对眼压进行年龄和多变量调整后，以及排除未诊断的青光眼病例后，均无变化。
在血压水平的临床范围内，眼压明显线性升高3mmHg；这种变化大于大多数其他全身和眼部参数。
