Klein B E, Klein R, Linton K L
Department of Ophthalmology, University of Wisconsin, Madison.
Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2224-8.
The Beaver Dam Eye Study is a population-based study of age-related eye diseases in persons 43-86 yr of age. Applanation tonometry was done on all study subjects. Mean intraocular pressure (IOP) increased significantly with age. Mean IOP differed little between the sexes and was not significantly different after age adjustment (in right eyes of 2721 women, it was 15.5 mm Hg, and in right eyes of 2135 men, it was 15.3 mm Hg). There was an association of IOP with systolic and diastolic blood pressures, body mass index, hematocrit, serum glucose, glycohemoglobin, cholesterol level, pulse, nuclear sclerosis, season, and time of day of measurement. These data confirm that, in a general population, IOP is associated with important systemic and ocular characteristics. Those characteristics should be considered in further research on determinants of IOP.
比弗迪姆眼研究是一项针对43至86岁人群中与年龄相关眼病的基于人群的研究。对所有研究对象进行了压平眼压测量。平均眼压（IOP）随年龄显著升高。男女之间的平均眼压差异不大，年龄调整后也无显著差异（在2721名女性的右眼，为15.5毫米汞柱，在2135名男性的右眼，为15.3毫米汞柱）。眼压与收缩压和舒张压、体重指数、血细胞比容、血糖、糖化血红蛋白、胆固醇水平、脉搏、核硬化、季节以及测量的时间有关。这些数据证实，在普通人群中，眼压与重要的全身和眼部特征相关。在进一步研究眼压的决定因素时应考虑这些特征。
