Kong Wei, Rollins Dennis L, Ideker Raymond E, Smith William M
Biomedical Engineering Department, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
IEEE Trans Biomed Eng. 2005 Jul;52(7):1365-7. doi: 10.1109/TBME.2005.847560.
We have developed a sonomicrometer and continuous wavelength (CW) Doppler flowmeter for a multichannel telemetry system. These developments will enable us to measure ventricular dimension and coronary artery blood velocity, which are valuable parameters to characterize sudden cardiac death (SCD) in ambulatory animal models of ventricular arrhythmias. The design goals for the sensors were accuracy, low power consumption, small size and compatibility with each other. The circuits were designed successfully and tested simultaneously in vivo. The CW Doppler flowmeter draws 9 mA and the sonomicrometer draws 28 mA on a 5-V supply. The ability to measure heart dimension and blood velocity will add significantly to our understanding of the sequence of events leading up to spontaneous sudden cardiac death.
我们为多通道遥测系统开发了一种超声心动图仪和连续波长(CW)多普勒流量计。这些进展将使我们能够测量心室尺寸和冠状动脉血流速度,而这是在动态室性心律失常动物模型中表征心脏性猝死(SCD)的重要参数。传感器的设计目标是准确性、低功耗、小尺寸以及相互兼容性。电路设计成功并在体内同时进行了测试。CW多普勒流量计在5V电源下的电流消耗为9mA,超声心动图仪为28mA。测量心脏尺寸和血流速度的能力将极大地增进我们对导致自发性心脏性猝死的一系列事件的理解。