Sistermann R, Möllenhoff G, Walz M, Josten C, Muhr G
Chirurgische Universitätsklinik und Poliklinik, Berufsgenossenschaftliche Krankenanstalten Bergmannsheil, Bochum.
Unfallchirurg. 1992 May;95(5):254-8.
The specific cellular host defence in patients with chronic post-traumatic bone infection was analyzed in a prospective study. The study included 120 patients with chronic post-traumatic osteomyelitis and 60 healthy volunteers. The number of CD-5, CD-4, CD-8, natural killer cells and the CD-4/CD-8 ratio were significantly decreased. The immunodeficiency seems to be trauma-induced and reinflammation seems to be due to other immunodeficient factors. The potential key role of a defect in cytokines is discussed.
在一项前瞻性研究中，分析了慢性创伤后骨感染患者特定的细胞宿主防御机制。该研究纳入了120例慢性创伤后骨髓炎患者和60名健康志愿者。CD-5、CD-4、CD-8、自然杀伤细胞数量以及CD-4/CD-8比值均显著降低。免疫缺陷似乎是由创伤引起的，而再发炎症似乎是由于其他免疫缺陷因素所致。文中讨论了细胞因子缺陷的潜在关键作用。
