Frei Heiner, Everts Regula, von Ammon Klaus, Kaufmann Franz, Walther Daniel, Hsu-Schmitz Shu-Fang, Collenberg Marco, Fuhrer Katharina, Hassink Ralph, Steinlin Maja, Thurneysen André
Swiss Association of Homeopathic Physicians SAHP, Lucerne, Switzerland.
Eur J Pediatr. 2005 Dec;164(12):758-67. doi: 10.1007/s00431-005-1735-7. Epub 2005 Jul 27.
An increasing number of parents turn to homeopathy for treatment of their hyperactive child. Two publications, a randomised, partially blinded trial and a clinical observation study, conclude that homeopathy has positive effects in patients with attention deficit hyperactivity disorder (ADHD). The aim of this study was to obtain scientific evidence of the effectiveness of homeopathy in ADHD. A total of 83 children aged 6-16 years, with ADHD diagnosed using the Diagnostic and Statistical Manual of Mental Disorders-IV criteria, were recruited. Prior to the randomised, double blind, placebo controlled crossover study, they were treated with individually prescribed homeopathic medications. 62 patients, who achieved an improvement of 50% in the Conners' Global Index (CGI), participated in the trial. Thirteen patients did not fulfill this eligibility criterion (CGI). The responders were split into two groups and received either verum for 6 weeks followed by placebo for 6 weeks (arm A), or vice-versa (arm B). At the beginning of the trial and after each crossover period, parents reported the CGI and patients underwent neuropsychological testing. The CGI rating was evaluated again at the end of each crossover period and twice in long-term follow-up. At entry to the crossover trial, cognitive performance such as visual global perception, impulsivity and divided attention, had improved significantly under open label treatment (P<0.0001). During the crossover trial, CGI parent-ratings were significantly lower under verum (average 1.67 points) than under placebo (P =0.0479). Long-term CGI improvement reached 12 points (63%, P <0.0001).
The trial suggests scientific evidence of the effectiveness of homeopathy in the treatment of attention deficit hyperactivity disorder, particularly in the areas of behavioural and cognitive functions.
越来越多的家长转向顺势疗法来治疗他们患有多动症的孩子。两项出版物，一项随机、部分盲法试验和一项临床观察研究，得出结论认为顺势疗法对注意力缺陷多动障碍（ADHD）患者有积极作用。本研究的目的是获得顺势疗法治疗ADHD有效性的科学证据。共招募了83名6至16岁、根据《精神障碍诊断与统计手册》第四版标准诊断为ADHD的儿童。在随机、双盲、安慰剂对照交叉研究之前，他们接受了个体化开方的顺势疗法药物治疗。62名在康纳斯全球指数（CGI）中改善了50%的患者参与了试验。13名患者未达到该入选标准（CGI）。应答者被分为两组，一组接受6周的真药治疗，随后接受6周的安慰剂治疗（A组），另一组反之（B组）。在试验开始时以及每个交叉期后，家长报告CGI，患者接受神经心理学测试。在每个交叉期结束时以及长期随访中再次评估CGI评分。在进入交叉试验时，在开放标签治疗下，视觉整体感知、冲动性和分散注意力等认知表现有显著改善（P<0.0001）。在交叉试验期间，真药治疗下的CGI家长评分（平均1.67分）显著低于安慰剂治疗（P =0.0479）。长期CGI改善达到12分（63%，P <0.0001）。
该试验表明顺势疗法治疗注意力缺陷多动障碍有效性的科学证据，特别是在行为和认知功能方面。
