Subbe C P, Williams E, Fligelstone L, Gemmell L
Department of Critical Care, Wrexham Maelor Hospital, Wrexham, UK.
Ann R Coll Surg Engl. 2005 Jul;87(4):226-32. doi: 10.1308/003588405X50921.
Patients at risk of catastrophic deterioration are often identified too late. Delayed identification of sick patients and delayed referral to intensive care units might be associated with poor outcomes. The goal of the review is to assess the potential impact of systems that enable early detection of critically ill surgical patients.
A Medline search was performed in September 2004. Other articles were identified using the bibliographies of papers found through Medline. All interventional trials reviewing the effect of Critical Care Outreach and Medical Emergency Teams were reviewed.
There is evidence that simple algorithms based on bedside observations can identify a large proportion of sick patients on general wards. Non-randomised studies have shown mixed results on impact of these interventions on mortality, cardiopulmonary arrests and intensive care admissions. The majority of studies do not specifically address surgical patients. A ward-based randomised trial from the UK seems to suggest improved mortality following the introduction of a Critical Care Outreach service with an Early Warning Score.
The literature about Critical Care Outreach and Medical Emergency teams is characterised by methodological weaknesses. However there is a common suggestion that early detection might improve outcome of critically ill surgical patients.
有发生灾难性病情恶化风险的患者往往在很晚才被识别出来。对病情严重患者的识别延迟以及转诊至重症监护病房的延迟可能与不良预后相关。本综述的目的是评估能够早期发现危重症外科患者的系统的潜在影响。
2004年9月进行了Medline检索。通过Medline检索到的论文参考文献中找出了其他文章。对所有评估重症监护外展服务和医疗急救团队效果的干预性试验进行了综述。
有证据表明,基于床边观察的简单算法能够识别普通病房中大部分病情严重的患者。非随机研究表明,这些干预措施对死亡率、心肺骤停及入住重症监护病房的影响结果不一。大多数研究并未专门针对外科患者。英国一项基于病房的随机试验似乎表明,引入带有早期预警评分的重症监护外展服务后死亡率有所改善。
关于重症监护外展服务和医疗急救团队的文献存在方法学上的缺陷。然而,普遍认为早期发现可能会改善危重症外科患者的预后。