Sherlin Leslie, Congedo Marco
Harold Able School of Psychology, Capella University, Minneapolis, MN, USA.
Neurosci Lett. 2005 Oct 21;387(2):72-4. doi: 10.1016/j.neulet.2005.06.069.
Electroencephalographic mapping techniques have been used to show differences between normal subjects and those diagnosed with various mental disorders. To date, there is no other research using the techniques of low-resolution brain electromagnetic tomography (LORETA) with the obsessive-compulsive disorder (OCD) population. The current investigation compares current source density measures of persons with OCD symptoms to an age-matched control group. The main finding is excess current source density in the Beta frequencies in the cingulate gyrus. This Beta activity is primarily located in the middle cingulate gyrus as well as adjacent frontal parieto-occipital regions. Lower frequency Beta is prominent more anteriorly in the cingulate gyrus whereas higher frequency Beta is seen more posteriorly. These preliminary findings indicate the utility of LORETA as a clinical and diagnostic tool.
脑电图测绘技术已被用于显示正常受试者与被诊断患有各种精神障碍的受试者之间的差异。迄今为止，尚无其他研究将低分辨率脑电磁断层扫描（LORETA）技术用于强迫症（OCD）人群。本研究将有强迫症症状的人的电流源密度测量结果与年龄匹配的对照组进行比较。主要发现是扣带回中β频段的电流源密度过高。这种β活动主要位于扣带回中部以及相邻的额顶枕区域。低频β在扣带回中更靠前的位置较为突出，而高频β在更靠后的位置可见。这些初步发现表明LORETA作为一种临床和诊断工具的实用性。
