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死后脑脊液中的有机酸

Organic acids in post-mortem cerebrospinal fluid.

作者信息

Coude M, Kamoun P

机构信息

Laboratoire de Biochimie médicale B, Hôpital Necker Enfants malades, France.

出版信息

Clin Chim Acta. 1992 Mar 31;206(3):201-6. doi: 10.1016/0009-8981(92)90089-9.

DOI:10.1016/0009-8981(92)90089-9
PMID:1606706
Abstract

Organic acids of cerebrospinal fluid (CSF) have been determined by gas chromatography-mass spectrometry in 29 post-mortem samples obtained from infants and 10 samples obtained from hospitalized children, as controls. Though the organic acids profile was similar in the two groups, eight organic acids not observed in CSF from live infants were inconstantly found in post-mortem CSF and for three of them, malic acid, lactyllactic acid and uracile, concentrations were correlated with the delay in sampling.

摘要

通过气相色谱-质谱法测定了29份取自婴儿的死后样本以及10份取自住院儿童的样本(作为对照)中的脑脊液(CSF)有机酸。尽管两组的有机酸谱相似,但在生前婴儿脑脊液中未观察到的8种有机酸在死后脑脊液中时有发现,其中苹果酸、乳乳酸和尿嘧啶这三种有机酸的浓度与采样延迟相关。

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Cerebrospinal fluid organic acids in biotinidase deficiency.
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