Gwon A E, Jones R L, Gruber L J, Mantras C
University of California, Irvine.
Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2279-83.
Secondary cataract growth commonly occurs after extracapsular cataract extraction. The proliferation of this regrowth occurs at rates related to many factors. In this study, the authors analyzed the amount of lens regeneration after endocapsular lens extraction that leaves the anterior and posterior capsules relatively intact. The analysis was performed in New Zealand albino rabbits with the aid of image analysis measurements in young and adult animals. The effect of low vacuum suction of the anterior capsule on the growth was determined. Lens regeneration was used as a measure of the growth potential of the leftover epithelial cells in the capsule bag. The results showed that lens regeneration was significantly faster in younger rabbits. However, low vacuum suction had no effect on the growth rate. Potential therapeutic agents for preventing secondary cataracts may be better analyzed with image analysis processing of lens regeneration, a precise and rapid measurement technique.
后发性白内障通常在囊外白内障摘除术后发生。这种再生的增殖速度与许多因素有关。在本研究中，作者分析了囊内晶状体摘除术后晶状体的再生量，该手术使前后囊相对完整。借助图像分析测量，对新西兰白化兔的幼兔和成年兔进行了分析。确定了前囊低真空抽吸对生长的影响。晶状体再生被用作囊袋中剩余上皮细胞生长潜力的指标。结果表明，幼兔的晶状体再生明显更快。然而，低真空抽吸对生长速度没有影响。通过晶状体再生的图像分析处理，一种精确而快速的测量技术，可能会更好地分析预防后发性白内障的潜在治疗药物。
