Gerdes A M, Callas G, Kasten F H
Am J Anat. 1979 Dec;156(4):523-31. doi: 10.1002/aja.1001560406.
Data are reported which show significant regional capillary differences in left ventricular endocardium and epicardium of normal rats and of rats with hyperthyroid-induced cardiac hypertrophy. The epicardial region of control rats has 38% more capillaries than the endocardial region. Control endocardial myocytes are 62% larger in cross-sectional area than epicardial myocytes. Hypertrophic hearts exhibit regional differences in capillary density similar to those in the normal hearts, but there is an overall reduction of 12 and 17.5% in capillary density in both regions. The average cross-sectional area of myocytes increases 34.5% in the epicardium and 22.5% in the endocardium.
所报告的数据显示，正常大鼠以及甲状腺功能亢进诱发心脏肥大的大鼠的左心室心内膜和心外膜存在显著的区域毛细血管差异。对照大鼠的心外膜区域毛细血管比心内膜区域多38%。对照心内膜心肌细胞的横截面积比心外膜心肌细胞大62%。肥大心脏的毛细血管密度区域差异与正常心脏相似，但两个区域的毛细血管密度总体分别降低了12%和17.5%。心肌细胞的平均横截面积在心外膜增加了34.5%，在心内膜增加了22.5%。
