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眼睑痉挛患者的吞咽障碍

Swallowing disorders in patients with blepharospasm.

作者信息

Cersósimo María G, Juri Silvia, Suárez de Chandler Silvia, Clerici Roxana, Micheli Federico E

机构信息

Programa de Parkinson y Movimientos Anormales, Instituto de Neurociencias, Universidad de Buenos Aires.

出版信息

Medicina (B Aires). 2005;65(2):117-20.

Abstract

Blepharospasm is a focal dystonia characterized by involuntary eye closure due to abnormal contraction of orbicular eyelid muscles. When blepharospasm is associated to the presence of involuntary oromandibular movements, it is termed Meige syndrome. The aim of this study was to investigate the presence of deglutition alterations in patients with concurrent blepharospasm and Meige syndrome. Twenty consecutive patients were studied by video fluoroscopy using a barium technique. The 4 stages of deglutition were investigated. Ninety percent of patients (18 cases) presented deglutition disorders. The more commonly found alterations were premature food drop, 15 cases (83%) and vallecuale residuals, 14 cases (78%). Sixty seven percent of abnormal findings occurred in the third stage of deglutition. Eighty-nine percent of patients (16) presented more than one swallowing alteration. There was a positive and significant correlation between the number of alterations and patient's age or disease duration. Prevalence of swallowing disorders in the healthy elderly population is reported to be 44%. In our series it reached 90%, suggesting that our findings might be related not only with age but also with a more widespread dystonia exceeding the orofacial muscles.

摘要

眼睑痉挛是一种局灶性肌张力障碍,其特征是由于眼轮匝肌异常收缩导致不自主闭眼。当眼睑痉挛伴有不自主的口下颌运动时,则称为梅杰综合征。本研究的目的是调查同时患有眼睑痉挛和梅杰综合征的患者是否存在吞咽改变。采用钡剂技术通过视频荧光透视对连续20例患者进行了研究。对吞咽的4个阶段进行了调查。90%的患者(18例)存在吞咽障碍。最常见的改变是过早食物掉落,15例(83%),以及梨状窝残留,14例(78%)。67%的异常发现在吞咽的第三阶段出现。89%的患者(16例)存在不止一种吞咽改变。改变的数量与患者年龄或病程之间存在正相关且具有显著相关性。据报道,健康老年人群中吞咽障碍的患病率为44%。在我们的系列研究中,这一比例达到了90%,这表明我们的发现可能不仅与年龄有关,还与一种超出口面部肌肉范围的更广泛的肌张力障碍有关。

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