Yeung K W K, Poon R W Y, Liu X Y, Ho J P Y, Chung C Y, Chu P K, Lu W W, Chan D, Cheung K M C
Division of Spine Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Faculty of Medicine, The University of Hong Kong, 5/F Professorial Block, Pokfulam, Hong Kong.
J Biomed Mater Res A. 2005 Nov 1;75(2):256-67. doi: 10.1002/jbm.a.30413.
Nickel-titanium shape memory alloys are promising materials in orthopedic applications because of their unique properties. However, for prolonged use in a human body, deterioration of the corrosion resistance of the materials becomes a critical issue because of the increasing possibility of deleterious ions released from the substrate to living tissues. We have investigated the use of nitrogen, acetylene, and oxygen plasma immersion ion implantation (PIII) to improve the corrosion resistance and mechanical properties of the materials. Our results reveal that the corrosion resistance and mechanical properties such as hardness and elastic modulus are significantly enhanced after surface treatment. The release of nickel is drastically reduced as compared with the untreated control. In addition, our in vitro tests show that the plasma-treated surfaces are well tolerated by osteoblasts. Among the three types of samples, the best biological effects are observed on the nitrogen PIII samples.
镍钛形状记忆合金因其独特性能，在骨科应用中是很有前景的材料。然而，对于在人体中的长期使用，由于从基体释放到活组织中的有害离子的可能性增加，材料耐腐蚀性的恶化成为一个关键问题。我们研究了使用氮、乙炔和氧等离子体浸没离子注入（PIII）来提高材料的耐腐蚀性和机械性能。我们的结果表明，表面处理后，耐腐蚀性以及诸如硬度和弹性模量等机械性能显著增强。与未处理的对照相比，镍的释放量大幅降低。此外，我们的体外试验表明，成骨细胞对经等离子体处理的表面耐受性良好。在这三种类型的样品中，在氮PIII样品上观察到最佳的生物学效应。
