Rupérez Elisa, Manero José María, Bravo-González Luis-Alberto, Espinar Eduardo, Gil F J
Centre de Recerca Nanoenginyeria (CrnE), Departamento Ciencia de los Materiales e Ingeniería Metalúrgica, Escola Tècnica Superior d'Enginyeria Industrial de Barcelona (ETSEIB), Universidad Politécnica de Catalunya, Barcelona 08028, Spain.
Unidad Docente de Ortodoncia, Facultad de Odontología, Universidad de Murcia, Murcia 30003, Spain.
Materials (Basel). 2016 May 24;9(6):402. doi: 10.3390/ma9060402.
A bioactive layer, free of nickel, has been performed for its greater acceptability and reliability in clinical applications for NiTi shape memory alloys. In the first step, a safe barrier against Ni release has been produced on the surface by means of a thicker rutile/anastase protective layer free of nickel. In the second step, a sodium alkaline titanate hydrogel, which has the ability to induce apatite formation, has been performed from oxidized surface. An improvement of host tissue-implant integration has been achieved in terms of Ni ions release and the bioactivity of the treated NiTi alloys has been corroborated with both and studies. The transformation temperatures (A, A, M, and M), as well as the critical stresses (σ), have been slightly changed due to this surface modification. Consequently, this fact must be taken into account in order to design new surface modification on NiTi implants.
已为镍钛形状记忆合金在临床应用中具有更高的可接受性和可靠性而制备了不含镍的生物活性层。第一步，通过较厚的无镍金红石/锐钛矿保护层在表面上形成了防止镍释放的安全屏障。第二步，从氧化表面制备了具有诱导磷灰石形成能力的碱性钛酸钠水凝胶。在镍离子释放方面实现了宿主组织与植入物整合的改善，并且通过 和 研究证实了经处理的镍钛合金的生物活性。由于这种表面改性，转变温度（A、A、M和M）以及临界应力（σ）略有变化。因此，在设计镍钛植入物的新表面改性时必须考虑到这一事实。
