Prasad Karthika, Bazaka Olha, Chua Ming, Rochford Madison, Fedrick Liam, Spoor Jordan, Symes Richard, Tieppo Marcus, Collins Cameron, Cao Alex, Markwell David, Ostrikov Kostya Ken, Bazaka Kateryna
School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane, QLD 4000, Australia.
CSIRO-QUT Joint Sustainable Processes and Devices Laboratory, Commonwealth Scientific and Industrial Research Organization, P.O. Box 218, Lindfield, NSW 2070, Australia.
Materials (Basel). 2017 Jul 31;10(8):884. doi: 10.3390/ma10080884.
Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.
金属生物材料是经过设计的系统，旨在为生物组织提供内部支撑，并且主要用于关节置换、牙植入物、骨科固定和支架。由于植入物整合不良、炎症、机械不稳定、坏死和感染，以及随之而来的患者护理时间延长、疼痛和功能丧失，生物材料使用量的增加与植入物相关并发症的发生率上升有关。在本综述中，我们将简要探讨金属生物材料的主要代表，以及用于改善生物金属的生物整合、机械强度和柔韧性的现有和新兴的表面及整体改性关键策略，并讨论它们与3D打印概念的兼容性。
