Heitkemper M, Jarrett M, Burr R, Cain K C, Landis C, Lentz M, Poppe A
Department of Biobehavioral Nursing and Health Systems, University of Washington, Seattle, WA 357266, USA.
Neurogastroenterol Motil. 2005 Aug;17(4):523-30. doi: 10.1111/j.1365-2982.2005.00700.x.
Patients with irritable bowel syndrome (IBS) commonly report sleep disturbances. This study examined self-report (Pittsburgh Sleep Quality Inventory) sleep quality and polysomnography (PSG) sleep variables in 18 women with mild-to-moderate IBS, 18 with severe IBS and 38 with age- and gender-matched controls. All women were studied on two consecutive nights in a sleep research laboratory where PSG data were collected. Retrospective and daily measures were obtained of self-reported sleep quality, psychological distress and gastrointestinal symptoms across one menstrual cycle. Self-report measures of psychological distress and sleep quality were significantly worse in the IBS-severe (IBS-S) group compared with controls. Rapid eye movement (REM) latency was higher in the two IBS groups on Night 1 than the control group (P = 0.06). Percentage time in REM was highest in the IBS-S on Night 2. All groups demonstrated greater sleep disruption on Night 1 (adaptation) when compared with Night 2. These results highlight the importance of considering the 'first-night effect' in those with IBS and the lack of concordance between self-report and objective indices of sleep in women with IBS.
肠易激综合征（IBS）患者常报告有睡眠障碍。本研究调查了18名轻度至中度IBS女性、18名重度IBS女性以及38名年龄和性别匹配的对照者的自我报告（匹兹堡睡眠质量指数）睡眠质量和多导睡眠图（PSG）睡眠变量。所有女性在睡眠研究实验室连续两晚接受研究，期间收集PSG数据。回顾性及日常测量获取了一个月经周期内自我报告的睡眠质量、心理困扰和胃肠道症状。与对照组相比，重度IBS（IBS-S）组的心理困扰和睡眠质量的自我报告测量结果明显更差。在第1晚，两个IBS组的快速眼动（REM）潜伏期均高于对照组（P = 0.06）。在第2晚，IBS-S组的REM睡眠时间百分比最高。与第2晚相比，所有组在第1晚（适应期）的睡眠干扰都更大。这些结果凸显了在IBS患者中考虑“首夜效应”的重要性，以及IBS女性自我报告与睡眠客观指标之间缺乏一致性。
