大肠杆菌O26:H11和O26:NM的分子谱分析及表型分析：肠出血性和肠致病性分离株的长期及地理一致性
Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates.
作者信息
Bielaszewska Martina, Zhang Wenlan, Tarr Phillip I, Sonntag Anne-Katharina, Karch Helge
机构信息
Institute for Hygiene and the National Consulting Laboratory on Hemolytic Uremic Syndrome, University Hospital Münster, Robert Koch Str. 41, 48149 Münster, Germany.
出版信息
J Clin Microbiol. 2005 Aug;43(8):4225-8. doi: 10.1128/JCM.43.8.4225-4228.2005.
Abstract
Fifty-eight enterohemorrhagic Escherichia coli O26:H11 or O26:NM (nonmotile) strains and 44 atypical enteropathogenic E. coli O26:H11 or O26:NM strains isolated from patients in 11 countries during 52 years share a common pool of non-stx virulence genes, fitness loci, and genotypic and phenotypic diagnostic markers. These findings indicate close relatedness between these pathotypes and provide a basis for their clinical laboratory diagnosis.
摘要
在52年间从11个国家的患者中分离出的58株肠出血性大肠杆菌O26:H11或O26:NM（无动力）菌株以及44株非典型肠致病性大肠杆菌O26:H11或O26:NM菌株，共享一组非stx毒力基因、适应性位点以及基因型和表型诊断标志物。这些发现表明这些致病型之间存在密切关联，并为它们的临床实验室诊断提供了依据。
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