剪接错位。

Splicing misplaced.

作者信息

Meshorer Eran, Misteli Tom

机构信息

National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

出版信息

Cell. 2005 Aug 12;122(3):317-8. doi: 10.1016/j.cell.2005.07.016.

DOI:10.1016/j.cell.2005.07.016

PMID:16096050

Abstract

Newly synthesized transcripts are usually spliced during transcription or immediately thereafter. So pre-mRNA splicing has been presumed to occur exclusively in the cell nucleus. In this issue of Cell, Denis et al. (2005) now report the presence of functional spliceosomes and signal-dependent pre-mRNA splicing in the cytoplasm of platelets.

摘要

新合成的转录本通常在转录过程中或之后立即进行剪接。因此，人们一直认为前体mRNA剪接仅发生在细胞核中。在本期《细胞》杂志中，德尼等人（2005年）现在报道了血小板细胞质中存在功能性剪接体和信号依赖性前体mRNA剪接。