Kim Cheol Hwan, Shin Ho Cheol, Won Chang Won
Department of Family Medicine, Sungkyunkwan University School of Medicine, Korea.
J Korean Med Sci. 2005 Aug;20(4):529-34. doi: 10.3346/jkms.2005.20.4.529.
There have been many epidemiological and clinical researches on chronic fatigue (CF) and chronic fatigue syndrome (CFS) since the 1990s, but such studies have been quite limited in Korea. The aim of this study was to investigate the point prevalence of CF and CFS in patients who visited community-based eight primary care clinics in Korea. The study subjects were 1,648 patients aged 18 yr and over who visited one of eight primary care clinics in Korea between the 7th and 17th of May 2001. The physicians determined the status of the subjects through fatigue-related questionnaires, medical history, physical examination, and laboratory tests. The subjects were categorized into no fatigue, prolonged fatigue, CF and then CF were further classified to medically explained CF (Physical CF and Psychological CF) and medically unexplained CF (CFS and idiopathic chronic fatigue). The point prevalence of CF and CFS were 8.4% (95% CI 7.1-9.7%) and 0.6% (95% CI 0.2-1.0%). Medically explained CF was 80.5% of CF, of which 57.1% had psychological causes. The clinical characteristics of CFS were distinguished from explained CF. CF was common but CFS was rare in community-based primary care settings in Korea.
自20世纪90年代以来，针对慢性疲劳（CF）和慢性疲劳综合征（CFS）开展了许多流行病学和临床研究，但在韩国此类研究相当有限。本研究旨在调查韩国社区8家基层医疗诊所就诊患者中CF和CFS的时点患病率。研究对象为2001年5月7日至17日期间在韩国8家基层医疗诊所之一就诊的1648名18岁及以上患者。医生通过与疲劳相关的问卷、病史、体格检查和实验室检查来确定研究对象的状况。研究对象被分为无疲劳、长期疲劳、CF，然后CF进一步分为医学可解释的CF（身体性CF和心理性CF）和医学无法解释的CF（CFS和特发性慢性疲劳）。CF和CFS的时点患病率分别为8.4%（95%CI 7.1 - 9.7%）和0.6%（95%CI 0.2 - 1.0%）。医学可解释的CF占CF的80.5%，其中57.1%有心理原因。CFS的临床特征与可解释的CF有所不同。在韩国社区基层医疗环境中，CF常见但CFS罕见。
