Krotkiewski M, Aniansson A, Grimby G, Björntorp P, Sjöström L
Eur J Appl Physiol Occup Physiol. 1979;42(4):271-81. doi: 10.1007/BF00423297.
One-leg exercise of 5 weeks duration in 10 healthy middleaged women resulted in a significant increment of muscle force in the exercising leg and in a less, but at some angular velocities also significant, increase in the nonexercising leg. The thickness of subcutaneous tissue measured by ultrasound and skinfold caliper decreased, while muscle thickness increased in the exercising leg only. The increased thickness of muscle tissue was associated with an increase in the relative number and relative fiber area of type II fibers in the exercising leg. The mean fiber area of type IIB fibers increased significantly as well as the activity of lactate dehydrogenase and myokinase. The decrease of thickness of subcutaneous adipose tissue was not associated with a significant decrease in fat cell size and was probably due to geometrical factors secondary to hypertrophy of the underlying muscle. It is concluded that the relationship between lean and fat components of the human thigh is significantly influenced by changes in the activity of the thigh skeletal muscles, but a local dynamic strength training program can hardly be used for local emptying of the fat depot over the exercising muscles.
对10名健康中年女性进行为期5周的单腿锻炼，结果显示，锻炼腿的肌肉力量显著增加，非锻炼腿的肌肉力量也有增加，但增幅较小，不过在某些角速度下也很显著。通过超声和皮褶卡尺测量，仅锻炼腿的皮下组织厚度减小，而肌肉厚度增加。肌肉组织厚度的增加与锻炼腿中II型纤维的相对数量和相对纤维面积的增加有关。IIB型纤维的平均纤维面积以及乳酸脱氢酶和肌激酶的活性显著增加。皮下脂肪组织厚度的减小与脂肪细胞大小的显著减小无关，可能是由于深层肌肉肥大引起的几何因素所致。研究得出结论，大腿骨骼肌活动的变化对人体大腿瘦组织和脂肪组织之间的关系有显著影响，但局部动态力量训练计划很难用于锻炼肌肉上方脂肪库的局部排空。
