Kamasaki Tomoko, Arai Ritsuko, Osumi Masako, Mabuchi Issei
Division of Biology, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, 153-8902, Japan.
Nat Cell Biol. 2005 Sep;7(9):916-7. doi: 10.1038/ncb1295.
Longitudinal F-actin cables are thought to be important for transporting materials for polarized cell growth in fission yeast. We show that most F-actin in the cables is oriented such that the barbed end faces the nearest cell tip during interphase; however, this directionality is reversed during mitosis. These orientations of F-actin ensure proper transport of materials to growing sites during these cell-cycle stages.
纵向F-肌动蛋白束被认为对裂殖酵母中极化细胞生长的物质运输很重要。我们发现，束中的大多数F-肌动蛋白的取向是，在间期其带刺端朝向最近的细胞尖端；然而，在有丝分裂期间这种方向性会逆转。F-肌动蛋白的这些取向确保了在这些细胞周期阶段物质向生长位点的正确运输。
