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珍稀药用植物梭茎大戟的抗菌活性

Anti-bacterial activity of Euphorbia fusiformis--a rare medicinal herb.

作者信息

Natarajan D, Britto S John, Srinivasan K, Nagamurugan N, Mohanasundari C, Perumal G

机构信息

Rapinat Herbarium, St. Joseph's College (Autonomous), Tiruchirappalli 620002, Tamil Nadu, India.

出版信息

J Ethnopharmacol. 2005 Oct 31;102(1):123-6. doi: 10.1016/j.jep.2005.04.023.

DOI:10.1016/j.jep.2005.04.023
PMID:16159702
Abstract

Euphorbia fusiformis Buch.-Ham. ex. D.Don (Euphorbiaceae) is a rare medicinal herb. Aqueous and organic solvent extracts of the leaves and rootstocks were investigated for anti-bacterial properties by using disc diffusion and well-in agar methods, against pathogenic strains of Gram positive (Bacillus subtilis and Staphylococcus aureus) and Gram negative bacteria (Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhii A and Salmonella typhii B). The different extracts differed significantly in their anti-bacterial properties with the methanolic extract being very effective followed by acetone and chloroform extracts. Aqueous and ethanolic extract showed very least activity. The result highlights that rootstock extracts had good anti-bacterial properties than leaf extracts. The results of this study support the use of this plant in traditional medicine to treat fever, wound infections and intestinal disorders.

摘要

梭果大戟(大戟科)是一种珍稀草药。采用纸片扩散法和琼脂打孔法,对梭果大戟叶和根茎的水提取物及有机溶剂提取物针对革兰氏阳性菌(枯草芽孢杆菌和金黄色葡萄球菌)和革兰氏阴性菌(大肠杆菌、肺炎克雷伯菌、普通变形杆菌、铜绿假单胞菌、甲型副伤寒沙门氏菌和乙型副伤寒沙门氏菌)的致病菌株的抗菌特性进行了研究。不同提取物的抗菌特性差异显著,其中甲醇提取物效果非常显著,其次是丙酮提取物和氯仿提取物。水提取物和乙醇提取物的活性最低。结果表明,根茎提取物的抗菌性能优于叶提取物。本研究结果支持这种植物在传统医学中用于治疗发热、伤口感染和肠道疾病。

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