鼠疫耶尔森菌仅含脂质A的内毒素时仍可存活。
Yersinia pestis is viable with endotoxin composed of only lipid A.
作者信息
Tan Li, Darby Creg
机构信息
Department of Microbiology, University of Alabama at Birmingham, BBRB Box 19, 1530 3rd Avenue South, Birmingham, Alabama 35294-2170, USA.
出版信息
J Bacteriol. 2005 Sep;187(18):6599-600. doi: 10.1128/JB.187.18.6599-6600.2005.
Abstract
Lipopolysaccharide (LPS) is the major outer membrane component of gram-negative bacteria. The minimal LPS structure for viability of Escherichia coli and Salmonella enterica serovar Typhimurium is lipid A glycosylated with 3-deoxy-D-manno-octulosonic acid (Kdo) residues. Here we show that another member of the Enterobacteriaceae, Yersinia pestis, can survive without Kdo in its LPS.
摘要
脂多糖（LPS）是革兰氏阴性菌外膜的主要成分。大肠杆菌和鼠伤寒沙门氏菌血清型鼠伤寒亚种生存所需的最小LPS结构是被3-脱氧-D-甘露糖辛酸（Kdo）残基糖基化的脂质A。在此我们表明，肠杆菌科的另一个成员，鼠疫耶尔森菌，其LPS中没有Kdo也能存活。
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