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青少年癌症患者的精子库保存

Sperm banking in adolescent cancer patients.

作者信息

Edge B, Holmes D, Makin G

机构信息

Faculty of Medical and Human Sciences, University of Manchester, UK.

出版信息

Arch Dis Child. 2006 Feb;91(2):149-52. doi: 10.1136/adc.2005.075242. Epub 2005 Sep 20.

DOI:10.1136/adc.2005.075242
PMID:16174641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2082672/
Abstract

BACKGROUND

Semen cryopreservation is a widely available method of maintaining fertility in male cancer patients. However this facility is not always used.

AIMS

To identify the barriers to successful sperm banking in a group of adolescent and young adult patients.

METHODS

Questionnaires were administered to 55 patients aged 13-21 years who had received potentially gonadotoxic therapy between 1997 and 2001 and had been offered sperm banking.

RESULTS

Forty five questionnaires were completed; 67% of respondents were able to bank sperm. Those who had been unsuccessful were younger and described higher levels of anxiety at diagnosis and greater difficulty in talking about fertility. They also described less understanding of sperm banking at the time of diagnosis.

CONCLUSION

Most adolescent cancer patients who have been offered fertility preservation are able to bank sperm. Younger patients may be helped by the provision of high quality information and more open discussion of the technique.

摘要

背景

精液冷冻保存是一种广泛应用于维持男性癌症患者生育能力的方法。然而,这种方法并非总是被采用。

目的

确定一组青少年和青年成年患者成功进行精子库保存的障碍。

方法

对55名年龄在13至21岁之间的患者进行问卷调查,这些患者在1997年至2001年期间接受了可能具有性腺毒性的治疗,并已被提供精子库保存服务。

结果

45份问卷得以完成;67%的受访者能够保存精子。那些未成功保存精子的患者年龄较小,在诊断时表现出更高的焦虑水平,并且在谈论生育问题时困难更大。他们还表示在诊断时对精子库保存的了解较少。

结论

大多数被提供生育力保存服务的青少年癌症患者能够保存精子。为年轻患者提供高质量信息并更开放地讨论该技术可能会有所帮助。

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本文引用的文献

1
Fertility preservation in adolescent males with cancer in the United Kingdom: a survey of practice.英国青少年癌症男性患者的生育力保存:一项实践调查
Arch Dis Child. 2004 Aug;89(8):736-7. doi: 10.1136/adc.2003.042036.
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Sperm banking and fertility concerns: enhancing practice and the support available to men with cancer.精子库与生育问题:改善针对癌症男性的医疗实践及支持服务
Eur J Oncol Nurs. 2000 Mar;4(1):55-8. doi: 10.1054/ejon.2000.0078.
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Preservation of fertility in children treated for cancer.癌症患儿生育力的保存
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Semen cryopreservation, utilisation and reproductive outcome in men treated for Hodgkin's disease.霍奇金病男性患者的精液冷冻保存、利用及生殖结局
Br J Cancer. 2002 Aug 12;87(4):381-4. doi: 10.1038/sj.bjc.6600483.
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Oncologists' attitudes and practices regarding banking sperm before cancer treatment.肿瘤学家关于癌症治疗前储存精子的态度和做法。
J Clin Oncol. 2002 Apr 1;20(7):1890-7. doi: 10.1200/JCO.2002.07.174.
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Knowledge and experience regarding cancer, infertility, and sperm banking in younger male survivors.年轻男性癌症幸存者关于癌症、不育症和精子库的知识与经验。
J Clin Oncol. 2002 Apr 1;20(7):1880-9. doi: 10.1200/JCO.2002.07.175.
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Fertility preservation for children treated for cancer (1): scientific advances and research dilemmas.癌症患儿的生育力保存(1):科学进展与研究困境
Arch Dis Child. 2001 Apr;84(4):355-9. doi: 10.1136/adc.84.4.355.
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Gonadal and sexual function in men treated for childhood cancer.接受儿童癌症治疗的男性的性腺和性功能。
Med Pediatr Oncol. 2000 Jul;35(1):52-63. doi: 10.1002/1096-911x(200007)35:1<52::aid-mpo9>3.0.co;2-y.
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Cryopreservation of semen from pubertal boys with cancer.癌症青春期男孩精液的冷冻保存
Med Pediatr Oncol. 2000 Mar;34(3):191-4. doi: 10.1002/(sici)1096-911x(200003)34:3<191::aid-mpo5>3.0.co;2-q.