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心脏直视手术后的长期通气支持。

Prolonged ventilatory support after open-heart surgery.

作者信息

LoCicero J, McCann B, Massad M, Joob A W

机构信息

Section of General Thoracic Surgery, Northwestern University Medical School, Chicago, IL.

出版信息

Crit Care Med. 1992 Jul;20(7):990-2. doi: 10.1097/00003246-199207000-00015.

Abstract

OBJECTIVES

To characterize the course of open-heart surgery patients who require prolonged (greater than 72 hrs) mechanical ventilation and to define the role and timing of tracheostomy.

DESIGN

Retrospective review.

SETTING

Cardiac surgery ICU and surgery wards at a university hospital.

PATIENTS

All open-heart surgery patients during an 18-month period from January 1988 to July 1989 (n = 581). From this group, 58 patients (9.9%) required prolonged mechanical ventilation.

INTERVENTIONS

Study patients (n = 58) were followed through the course of intubation and/or tracheostomy until they were extubated, left the hospital on ventilation, or died.

MEASUREMENTS AND MAIN RESULTS

End-points for mortality and complications were determined. Overall mortality rate was 43% in the patients who required prolonged mechanical ventilation. Twenty-eight percent of the 58 patients died within the first 14 days. Of those patients who survived, 55% required an endotracheal tube only and were extubated in less than 14 days; 45% of the patients required tracheostomy. Of those patients who required tracheostomy, five (26%) were eventually extubated, seven (37%) remained mechanically ventilated, and seven (37%) died. The complication rate for endotracheal tubes was 65%; the complication rate for tracheostomy was 37%.

CONCLUSIONS

Open-heart surgery patients requiring prolonged mechanical ventilation are a desperately ill subset of cardiac surgery patients. Those patients who survive are either extubated in less than 14 days or require prolonged mechanical ventilation beyond that point. In our opinion, patients should be given 1 wk to recover and one trial of weaning from the ventilator. If this approach fails, then they should undergo elective tracheostomy.

摘要

目的

描述需要长时间(超过72小时)机械通气的心脏直视手术患者的病程,并确定气管切开术的作用和时机。

设计

回顾性研究。

地点

一所大学医院的心脏外科重症监护病房和外科病房。

患者

1988年1月至1989年7月这18个月期间的所有心脏直视手术患者(n = 581)。在该组中,58名患者(9.9%)需要长时间机械通气。

干预措施

对研究患者(n = 58)进行插管和/或气管切开术全程随访,直至拔管、带呼吸机出院或死亡。

测量指标和主要结果

确定死亡率和并发症的终点指标。需要长时间机械通气的患者总体死亡率为43%。58名患者中有28%在头14天内死亡。在存活的患者中,55%仅需要气管内插管,并在14天内拔管;45%的患者需要气管切开术。在需要气管切开术的患者中,5名(26%)最终拔管,7名(37%)仍需机械通气,7名(37%)死亡。气管内插管的并发症发生率为65%;气管切开术的并发症发生率为37%。

结论

需要长时间机械通气的心脏直视手术患者是心脏手术患者中病情极其严重的一部分。存活的患者要么在14天内拔管,要么在此之后需要长时间机械通气。我们认为,应给予患者1周时间恢复,并进行一次脱机尝试。如果这种方法失败,那么他们应接受择期气管切开术。

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