Poelmans S, De Wasch K, Noppe H, Van Hoof N, Van Cruchten S, Le Bizec B, Deceuninck Y, Sterk S, Van Rossum H J, Hoffman M K, De Brabander H F
Laboratory of Chemical Analysis, Research Group of Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Salisburylaan, 133 B-9820 Merelbeke, Belgium.
Food Addit Contam. 2005 Sep;22(9):808-15. doi: 10.1080/02652030500197805.
Following findings of 17beta-19-nortestosterone (150-200 microg kg(-1)) in pigs of unspecified gender imported into the European Union, a study to determine steroid and hormone levels in swine from six age/gender categories (uncastrated 'old' boars, cryptorchids, one intersex, barrows, gilts and sows) was initiated. Indeed, for some hormones there has been a discussion about their being endo- or exogenous. Tissue and urine samples from swine from each of the six categories were obtained in Belgium, France, the Netherlands and the USA. Samples were analysed in three laboratories. Quantitation was obtained for norandrostenedione, 19-nortestosterone and boldenone. The results give a well-documented overview of the status of the presence of these hormones in swine. The data illustrate that uncastrated 'old' boars produce the highest percentage of 'positive' matrices, followed by the cryptorchids. Concentrations in the matrices of the barrows and the gilts are lower. Also, sow matrices contain low amounts of nor-steroids. Furthermore, urine samples from an intersex pig contains a higher concentration of nortestosterone than sows and can therefore be suspected for illegal use of these hormones. Veterinarians taking samples in pig farms for the analysis of hormones need to be aware of the presence and concentrations of these substances in the different categories.
在进口到欧盟的未指明性别的猪中发现17β-19-去甲睾酮（150 - 200微克/千克）后，开展了一项研究，以确定来自六个年龄/性别类别的猪（未阉割的“成年”公猪、隐睾猪、一头雌雄同体猪、去势公猪、后备母猪和母猪）体内的类固醇和激素水平。事实上，对于某些激素，一直存在关于它们是内源性还是外源性的讨论。从比利时、法国、荷兰和美国获取了来自这六个类别的猪的组织和尿液样本。样本在三个实验室进行分析。对去甲雄烯二酮、19-去甲睾酮和勃地酮进行了定量分析。结果充分记录了这些激素在猪体内的存在状况。数据表明，未阉割的“成年”公猪产生“阳性”样本的比例最高，其次是隐睾猪。去势公猪和后备母猪样本中的浓度较低。此外，母猪样本中所含的去甲类固醇含量也很低。此外，一头雌雄同体猪的尿液样本中去甲睾酮的浓度高于母猪，因此可能涉嫌非法使用这些激素。在猪场采集样本用于激素分析的兽医需要了解这些物质在不同类别猪中的存在情况和浓度。
