Palm Asa, LoSasso Thomas
Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.
Med Phys. 2005 Aug;32(8):2434-42. doi: 10.1118/1.1949747.
The energy dependence of radiographic film can introduce dosimetric errors when evaluating photon beams. The variation of the film response, which is attributed to the changing photon spectrum with depth and field size, has been the subject of numerous publications in recent years. However, these data show large unexplained differences in the magnitude of this variation among independent studies. To try to resolve this inconsistency, this study assesses the dependence of radiographic film response on phantom material and phantom size using film measurements and Monte Carlo calculations. The relative dose measured with film exposed to 6 MV x rays in various phantoms (polystyrene, acrylic, Solid Water, and water; the lateral phantom dimensions vary from 25 to 50 cm square; backscatter thickness varies from 10 to 30 cm) is compared with ion chamber measurements in water. Ranges of field size (5 x 5 to 40 x 40 cm2) and depth (dmax to 20 cm) are studied. For similar phantom and beam configurations, Monte Carlo techniques generate photon fluence spectra from which the relative film response is known from an earlier study. Results from film response measurements agree with those derived from Monte Carlo calculations within 3%. For small fields (< or = 10 x 10 cm2) and shallow depths (< or = 10 cm) the film response variation is small, less than 4%, for all phantoms. However, for larger field sizes and depths, the phantom material and phantom size have a greater influence on the magnitude of the film response. The variation of film response, over the ranges of field sizes and depths studied, is 50% in polystyrene compared with 30% in water. Film responses in Solid Water and water phantoms are similar; acrylic is between water and polystyrene. In polystyrene the variation of film response for a 50 cm square phantom is nearly twice that observed in a 25 cm square phantom. This study shows that differences in the configuration of the phantoms used for film dosimetry can explain much of the inconsistency for film response reported in the literature.
在评估光子束时,射线照相胶片的能量依赖性可能会引入剂量测定误差。胶片响应的变化归因于光子能谱随深度和射野大小的改变,近年来已成为众多出版物的主题。然而,这些数据显示,独立研究之间在这种变化幅度上存在巨大的无法解释的差异。为了试图解决这种不一致性,本研究使用胶片测量和蒙特卡罗计算来评估射线照相胶片响应与模体材料和模体尺寸的依赖性。将在各种模体(聚苯乙烯、丙烯酸、固体水和水;模体横向尺寸从25平方厘米到50平方厘米不等;反向散射厚度从10厘米到30厘米不等)中用6兆伏X射线照射的胶片测量的相对剂量与水中电离室测量结果进行比较。研究了射野大小(5×5至40×40平方厘米)和深度(最大剂量深度至20厘米)范围。对于相似的模体和射束配置,蒙特卡罗技术生成光子注量能谱,根据早期研究可知相对胶片响应。胶片响应测量结果与蒙特卡罗计算结果在3%以内相符。对于小射野(≤10×10平方厘米)和浅深度(≤10厘米),所有模体的胶片响应变化都很小,小于4%。然而,对于更大的射野大小和深度,模体材料和模体尺寸对胶片响应幅度的影响更大。在所研究的射野大小和深度范围内,聚苯乙烯中胶片响应的变化为50%,而水中为30%。固体水和水模体中的胶片响应相似;丙烯酸介于水和聚苯乙烯之间。在聚苯乙烯中,50平方厘米模体的胶片响应变化几乎是25平方厘米模体中观察到的两倍。本研究表明,用于胶片剂量测定的模体配置差异可以解释文献中报道的胶片响应不一致的大部分情况。