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免疫复合物疾病中的血浆置换

Plasma exchange in immune complex disease.

作者信息

Houwert D A, Kater L, Hené R J, Struyvenberg A

出版信息

Proc Eur Dial Transplant Assoc. 1979;16:520-7.

PMID:162005
Abstract

The effect of plasma exchange on CIC, anti-dsDNA and complement levels and clinical activity was studied in eight patients with SLE, one with idiopathic anaphylactoid purpura and one with mixed cryoglobulinaemia. No association existed between different tests for immune complex detection. Plasma exchange as sole therapy was effective in patients with idiopathic anaphylactoid purpura and mixed cryoglobulinaemia, but not in one SLE patient with CIC. Five SLE patients with CIC treated with corticosteroids showed improvement on plasma exchange but in two patients with and two with CIC plasma exchange was not effective.

摘要

对8例系统性红斑狼疮患者、1例特发性类过敏性紫癜患者和1例混合性冷球蛋白血症患者,研究了血浆置换对循环免疫复合物(CIC)、抗双链DNA及补体水平和临床活性的影响。不同免疫复合物检测试验之间无相关性。血浆置换作为单一疗法对特发性类过敏性紫癜和混合性冷球蛋白血症患者有效,但对1例有CIC的系统性红斑狼疮患者无效。5例接受皮质类固醇治疗且有CIC的系统性红斑狼疮患者经血浆置换后病情改善,但另外2例有CIC的患者血浆置换无效。

相似文献

1
Plasma exchange in immune complex disease.免疫复合物疾病中的血浆置换
Proc Eur Dial Transplant Assoc. 1979;16:520-7.
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