[作为预防老年患者药物不良反应辅助工具的《比尔斯标准》]

[The Beers List as an aid to prevent adverse drug reactions in elderly patients].

作者信息

Vingerhoets R W, van Marum R J, Jansen P A F

机构信息

Universitair Medisch Centrum Utrecht, Divisie Interne Geneeskunde en Dermatologie, Zorgeenheid Geriatrie, huispostnr. Bo5.256, Postbus 85.500, 3508 GA Utrecht.

出版信息

Ned Tijdschr Geneeskd. 2005 Sep 17;149(38):2099-103.

PMID:16201599

Abstract

Elderly patients are highly susceptible for developing adverse drug reactions (ADR) that can lead to hospitalisation or death. Most of these ADR can be prevented if doctors adjust their prescriptions. Beers et al. have developed a list of drugs that should not be prescribed to elderly patients since they are known for their association with serious ADR. In The Netherlands, 20% of elderly patients receive drugs that are in the so-called Beers list. Although the Beers list has not been adjusted to the Dutch situation, avoidance of these drugs may reduce drug-related hospital admittance. Development of an improved list of drugs that should not be prescribed to elderly patients is needed that is applicable to The Netherlands.

摘要

老年患者极易发生药物不良反应（ADR），这些反应可能导致住院或死亡。如果医生调整处方，大多数这类药物不良反应是可以预防的。比尔斯等人制定了一份不应给老年患者开的药物清单，因为这些药物因与严重药物不良反应有关而闻名。在荷兰，20%的老年患者服用所谓比尔斯清单上的药物。尽管比尔斯清单尚未根据荷兰的情况进行调整，但避免使用这些药物可能会减少与药物相关的住院率。需要制定一份适用于荷兰的、改进后的不应给老年患者开的药物清单。