白 Lawsonia 提取物作为肝脏保护剂的评估。
An evaluation of Lawsonia alba extract as hepatoprotective agent.
作者信息
Anand K K, Singh B, Chand D, Chandan B K
机构信息
Department of Pharmacology, Regional Research Laboratory, Jammu Twai, India.
出版信息
Planta Med. 1992 Feb;58(1):22-5. doi: 10.1055/s-2006-961382.
PMID:1620739
Abstract
The hepatoprotective activity of an ethanol-water (1:1) extract of Lawsonia alba has been studied against CCl4-induced liver toxicity. The effects of the extract on hexobarbitone-induced sleep, BSP clearance, and on certain biochemical parameters indicated its protective role. There was no effect on bile flow. The extract did not show any signs of toxicity and the minimum lethal dose was greater than 2.0 g/kg p.o. in mice.
摘要
已对白花 Lawsonia 的乙醇 - 水（1:1）提取物针对四氯化碳诱导的肝毒性的保肝活性进行了研究。该提取物对己巴比妥诱导的睡眠、溴磺酚酞清除率以及某些生化参数的影响表明了其保护作用。对胆汁流量没有影响。该提取物未显示出任何毒性迹象，小鼠经口给药的最小致死剂量大于 2.0 g/kg。
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