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The future of bone healing.

作者信息

Cheung Catherine

出版信息

Clin Podiatr Med Surg. 2005 Oct;22(4):631-41. viii. doi: 10.1016/j.cpm.2005.07.002.

DOI:10.1016/j.cpm.2005.07.002
PMID:16213385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7118872/
Abstract

With more than 5.5 million fractures and 1 million bone repair surgeries annually, bone graft plays a significant role in aiding fracture repair. In the United States alone, surgeons perform an estimated 500,000 to 600,000 bone grafting procedures annually. With the advent of possibilities from bone substitutes, growth factors, and stem cell research, the potential for enhancing bone healing is vast. This article attempts to survey current trends and to highlight upcoming techniques in the future of bone healing.

摘要

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本文引用的文献

1
The mechanical or electrical induction of medullary angiogenesis: will it improve sternal wound healing?延髓血管生成的机械或电诱导：它会改善胸骨伤口愈合吗？
Tex Heart Inst J. 2004;31(4):363-7.
2
Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages.骨形态发生蛋白-2诱导胚胎干细胞向软骨、骨和脂肪细胞分化：辅助因子对分化谱系的影响
BMC Dev Biol. 2005 Jan 26;5:1. doi: 10.1186/1471-213X-5-1.
3
The 2003 Nicolas Andry Award. Orthopaedic gene therapy.2003年尼古拉斯·安德里奖。骨科基因治疗。
Clin Orthop Relat Res. 2004 Dec(429):316-29. doi: 10.1097/01.blo.0000148854.14399.ec.
4
Biological and biophysical principles in extracorporal bone tissue engineering. Part III.体外骨组织工程中的生物学和生物物理学原理。第三部分。
Int J Oral Maxillofac Surg. 2004 Oct;33(7):635-41. doi: 10.1016/j.ijom.2004.04.006.
5
Tissue engineering and cell based therapies, from the bench to the clinic: the potential to replace, repair and regenerate.从实验室到临床的组织工程和基于细胞的疗法：替代、修复和再生的潜力。
Reprod Biol Endocrinol. 2003 Nov 13;1:102. doi: 10.1186/1477-7827-1-102.
6
Adult mesenchymal stem cells and cell-based tissue engineering.成人间充质干细胞与基于细胞的组织工程
Arthritis Res Ther. 2003;5(1):32-45. doi: 10.1186/ar614. Epub 2002 Dec 11.
7
Efficacy of allogenic bone implants in a series of consecutive elective foot procedures.
J Foot Ankle Surg. 2003 Mar-Apr;42(2):86-9. doi: 10.1016/s1067-2516(03)70006-4.
8
Influence of diabetes mellitus on heart failure risk and outcome.糖尿病对心力衰竭风险及预后的影响。
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9
Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4.干细胞表达的血管内皮生长因子和骨形态发生蛋白-4对骨形成和愈合的协同增强作用。
J Clin Invest. 2002 Sep;110(6):751-9. doi: 10.1172/JCI15153.
10
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover.血管内皮生长因子通过促进血管生成和骨转换来刺激骨修复。
Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9656-61. doi: 10.1073/pnas.152324099. Epub 2002 Jul 12.