Campos M, Hertzog L, Garbus J J, McDonnell P J
Doheny Eye Institute, Los Angeles, CA 90033-1088.
Am J Ophthalmol. 1992 Jul 15;114(1):51-4. doi: 10.1016/s0002-9394(14)77412-4.
Corneal anesthesia or hypesthesia can complicate refractive surgical procedures such as epikeratophakia and radial keratotomy. An esthesiometer was used to measure the corneal sensitivity in unoperated-on corneas and fellow corneas after excimer laser photorefractive keratectomy. Decrease in corneal sensitivity was noted within six postoperative weeks, with mean sensitivity being 75.2% +/- 13.3% of normal. Within the first three postoperative months, the patients operated on for correction of compound astigmatism recovered 95.7% +/- 5.3% of the corneal sensitivity, whereas the patients operated on for correction of severe myopia recovered 86.2% +/- 11.2% (P = .07). None of the patients had delayed epithelial healing or recurrent corneal erosions during the time of decreased corneal sensitivity. In otherwise normal myopic eyes, photorefractive keratectomy measurably reduced corneal sensitivity for several postoperative weeks.
角膜麻醉或感觉减退会使诸如表层角膜镜片术和放射状角膜切开术等屈光手术变得复杂。使用角膜知觉计测量准分子激光屈光性角膜切削术后未手术角膜和对侧角膜的角膜敏感性。术后六周内发现角膜敏感性降低，平均敏感性为正常的75.2%±13.3%。术后前三个月内，接受复合散光矫正手术的患者恢复了95.7%±5.3%的角膜敏感性，而接受高度近视矫正手术的患者恢复了86.2%±11.2%（P = 0.07）。在角膜敏感性降低期间，没有患者出现上皮愈合延迟或复发性角膜糜烂。在其他方面正常的近视眼中，屈光性角膜切削术在术后数周内可显著降低角膜敏感性。
