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欧洲生物信息学研究所的植物微阵列数据。介绍AtMIAMExpress,一种用于向ArrayExpress提交拟南芥基因表达数据的工具。

Plant-based microarray data at the European Bioinformatics Institute. Introducing AtMIAMExpress, a submission tool for Arabidopsis gene expression data to ArrayExpress.

作者信息

Mukherjee Gaurab, Abeygunawardena Niran, Parkinson Helen, Contrino Sergio, Durinck Steffen, Farne Anna, Holloway Ele, Lilja Per, Moreau Yves, Oezcimen Ahmet, Rayner Tim, Sharma Anjan, Brazma Alvis, Sarkans Ugis, Shojatalab Mohammadreza

机构信息

EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

出版信息

Plant Physiol. 2005 Oct;139(2):632-6. doi: 10.1104/pp.105.063156.

Abstract

ArrayExpress is a public microarray repository founded on the Minimum Information About a Microarray Experiment (MIAME) principles that stores MIAME-compliant gene expression data. Plant-based data sets represent approximately one-quarter of the experiments in ArrayExpress. The majority are based on Arabidopsis (Arabidopsis thaliana); however, there are other data sets based on Triticum aestivum, Hordeum vulgare, and Populus subsp. AtMIAMExpress is an open-source Web-based software application for the submission of Arabidopsis-based microarray data to ArrayExpress. AtMIAMExpress exports data in MAGE-ML format for upload to any MAGE-ML-compliant application, such as J-Express and ArrayExpress. It was designed as a tool for users with minimal bioinformatics expertise, has comprehensive help and user support, and represents a simple solution to meeting the MIAME guidelines for the Arabidopsis community. Plant data are queryable both in ArrayExpress and in the Data Warehouse databases, which support queries based on gene-centric and sample-centric annotation. The AtMIAMExpress submission tool is available at http://www.ebi.ac.uk/at-miamexpress/. The software is open source and is available from http://sourceforge.net/projects/miamexpress/. For information, contact miamexpress@ebi.ac.uk.

摘要

ArrayExpress是一个基于微阵列实验最少信息(MIAME)原则建立的公共微阵列数据库,用于存储符合MIAME标准的基因表达数据。基于植物的数据集约占ArrayExpress中实验的四分之一。大多数数据集以拟南芥(Arabidopsis thaliana)为基础;然而,也有其他基于普通小麦(Triticum aestivum)、大麦(Hordeum vulgare)和杨树亚种(Populus subsp.)的数据集。AtMIAMExpress是一个基于网络的开源软件应用程序,用于将基于拟南芥的微阵列数据提交到ArrayExpress。AtMIAMExpress以MAGE-ML格式导出数据,以便上传到任何符合MAGE-ML标准的应用程序,如J-Express和ArrayExpress。它是为生物信息学专业知识最少的用户设计的工具,具有全面的帮助和用户支持,是满足拟南芥研究群体MIAME指南的一个简单解决方案。植物数据在ArrayExpress和数据仓库数据库中均可查询,这两个数据库支持基于基因中心和样本中心注释的查询。AtMIAMExpress提交工具可在http://www.ebi.ac.uk/at-miamexpress/获取。该软件是开源的,可从http://sourceforge.net/projects/miamexpress/获得。如需信息,请联系miamexpress@ebi.ac.uk。

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本文引用的文献

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Bioinformatics. 2001 Apr;17(4):369-70. doi: 10.1093/bioinformatics/17.4.369.

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